Tissue plasminogen activator, urokinase, and plasmin are important components of:

a. coagulation.

b. fibrinolysis.

c. platelet plug formation.

d. hemostasis.

Video transcript

Hey, everyone. Let's take a look at this question together which of the following components of fibrinolysis binds to fibrin and cleaves it at specific sites resulting in the dissolution of the clot. Is it answer choice. A eines answer choice. B plasminogen. Answer choice C tissue plasminogen, activator or answer choice. D plasmin. Let's work this problem out together to try to figure out which of the following answer choices is the component of fibro analysis that binds to fibrin and cleaves it at specific sites. So, in order to solve this question, we have to recall what we have learned about the different components of fibro analysis and which component binds to fibrin and cleaves it at specific sites. And we can recall that fibro analysis involves the activation of the inactive enzyme plasminogen, which we know that the inactive enzyme plasminogen is activated by enzymes like tissue plasminogen, activator and urokinase to activate plasminogen and turn it into plasmin, which plasmin acts on fibrin, breaking it down into smaller fragments called fibrin degradation products. So, fibrinolysis involves the activation of plasminogen into plat, which plasmin acts on fibrin and breaks it down into smaller fragments or cleaves it at specific sites resulting in the dissolution of the clot. So answer choice, D plasmin is the correct answer and all other answer choices are incorrect. I hope you found this video to be helpful. Thank you and goodbye.