Chapter 19, Problem 19.14a
What are the overall goals of the common pathway of coagulation?
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Platelets are derived from cells called:
a. thromboblasts.
b. leukoblasts.
c. megakaryocytes.
d. thrombokaryocytes.
Number the steps of hemostasis in order, putting 1 by the first event, 2 by the second, and so on.
____The intrinsic/contact activation and extrinsic/tissue factor pathways produce factor Xa.
____The clot retracts.
____Thrombin converts fibrinogen to fibrin, and fibrin glues the plug together.
____Platelets are activated, and the platelet plug forms.
____Vasoconstriction and increased tissue pressure decrease blood flow through the vessel.
____Tissue plasminogen activator activates plasmin, which degrades fibrin.
____The common pathway produces thrombin.
How do the intrinsic/contact activation and extrinsic/tissue factor coagulation pathways differ? How are they similar?
Which of the following is not an anticlotting agent produced by endothelial cells?
a. Prostacyclin
b. Protein C
c. Antithrombin-III
d. Warfarin
Tissue plasminogen activator, urokinase, and plasmin are important components of:
a. coagulation.
b. fibrinolysis.
c. platelet plug formation.
d. hemostasis.
Fill in the blanks: The two most clinically important groups of antigens on erythrocytes are the______and______blood groups.