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Ch. 20 The Lymphatic System and Immunity
Amerman - Human Anatomy & Physiology 2nd Edition
Amerman2nd EditionHuman Anatomy & PhysiologyISBN: 9780136873822Not the one you use?Change textbook
Chapter 20, Problem 7c

Mark the following statements as true or false. If a statement is false, correct it to make a true statement.
NK cells are cytotoxic cells that lyse and kill cancer cells and cells infected with certain viruses.

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Step 1: Understand the role of NK (Natural Killer) cells in the immune system. NK cells are a type of lymphocyte that play a critical role in the innate immune response. They are cytotoxic cells that target and destroy abnormal cells, such as cancer cells and cells infected with viruses.
Step 2: Evaluate the statement provided. The statement claims that NK cells are cytotoxic cells that lyse and kill cancer cells and cells infected with certain viruses. This aligns with the known function of NK cells in the immune system.
Step 3: Determine whether the statement is true or false. Based on the description of NK cells, the statement is true because it accurately describes their function.
Step 4: If the statement were false, you would need to correct it. For example, if the statement incorrectly described NK cells as part of the adaptive immune system, you would correct it by stating that NK cells are part of the innate immune system.
Step 5: Conclude that the statement is true and does not require correction, as it accurately reflects the role of NK cells in lysing and killing cancer cells and virus-infected cells.

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Key Concepts

Here are the essential concepts you must grasp in order to answer the question correctly.

Natural Killer (NK) Cells

Natural Killer (NK) cells are a type of lymphocyte in the immune system that play a crucial role in the body's defense against tumors and virally infected cells. They are part of the innate immune response and can recognize and destroy compromised cells without prior sensitization, making them essential for early immune responses.
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Cytotoxic Activity

Cytotoxic activity refers to the ability of certain immune cells, such as NK cells, to kill target cells, including cancerous and infected cells. This process involves the release of cytotoxic granules containing perforin and granzymes, which induce apoptosis (programmed cell death) in the target cells, thereby eliminating the threat to the organism.
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Immune Response

The immune response is the body's defense mechanism against pathogens, including viruses and cancer cells. It involves a complex interplay of various immune cells, signaling molecules, and mechanisms that work together to identify and eliminate harmful entities, ensuring the maintenance of health and homeostasis.
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