Intro to Fatty Acid Oxidation - Video Tutorials & Practice Problems
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concept
Intro to Fatty Acid Oxidation Concept 1
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In this video, we're gonna take a look at an intro to fatty acid oxidation. Now, here we're going to say that fatty acid oxidation is part of stage two of food metabolism. We're gonna say here it oxidizes fatty acids to yield acetyl coa and are high energy molecules in the form of N A DH and fa DH two. If we take a look here at the overview, we have our stage one, we're focusing on the digestion of our lipids and we're paying attention to the creation of our fatty acids. We're not paying attention to glycerol with our fatty acids. We have fatty acid activation which utilizes a TP to do this. So we're activating are fatty acid and this is happening within the cytosol under anaerobic respiration. From here, we would then head into stage two where we're dealing with the mitochondrial matrix. Here, beta oxidation occurs where we have the formation of our acetyl coa. Now, Aceto, Koe can have one of two possibilities or can continue on to stages three and four to the eventual production of A TP or we can have the formation of what we call ketone bodies, which we'll discuss later on. Now, here we're gonna say fatty acids are prepared or activated for oxidation within the cytosol. As we can see in our overview and oxidation takes place inside the mitochondrial matrix. So here we have our beta oxidation that occurs. So just remember that when we talk about fatty acid oxidation, it's occurring in stage two of food metabolism.
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example
Intro to Fatty Acid Oxidation Example 1
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Which of the following statements is not true for fatty acid oxidation. A fatty acid oxidation is a cab bolic process that degrades fatty acids to acetyl coa this statement is true. We do have the breaking down of lipids, the fatty acids and that eventually gets broken down into acetyl. Koa fatty acids are activated in the cytosol. That is true and oxidize inside the mitochondrial matrix. That is also true. Remember, we utilize a TP in order to activate our fatty acid within the cytosol and then when we get to the mitochondrial matrix, we undergo what's called beta oxidation to form our acetyl coa high energy molecules produced in fatty acid oxidation are fa DH two and N A DH. That is true. Fatty acid oxidation directly produces many A TP molecules. So the keyword here is directly, no, it doesn't directly make many A TP molecules here, right? So we never cited that as a feature when it comes to fatty oxidation. So this statement here would be incorrect later on. We'll see how exactly this works. But for now, we know that directly, it doesn't produce many A TP molecules
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concept
Intro to Fatty Acid Oxidation Concept 2
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Now, in this video, we'll talk about the phases of fatty acid oxidation. Now, fatty acid oxidation takes place in three successive phases. In phase A, we have what's called activation. Here. It prepares the fatty acid for oxidation by converting it into a fatty acyl coa to do this. We have to consume a TP. In phase B, we have what's called transport. Here. The fatty aae moves from the cytosol to the mitochondrial matrix to the connote carnatine shuttle and then phase C we have oxidation here. We're gonna have the beta oxidation pathway breaks the fatty acid chain into multiple acetyl Coates. In addition to this, it's gonna produce our high energy molecules in the form of fa DH two as well as N A DH. If we take a look at this overview, we start out with our fatty acid by consuming a TP. We're able to convert it into our fatty acyl coa, it then goes into our transport phase where it's transformed into our fatty ay carnitine. So car here and then finally, we have oxidation where it's going to be oxidized into multiple acetyl coa molecules. And in addition, are high energy molecules of, of FA DH two and N A DH. So this image gives us a good overview of what fatty acid oxidation entails.
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example
Intro to Fatty Acid Oxidation Example 2
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In this example, it says which of the following is an incorrect description of a phase in fatty acid oxidation. So remember there's three phases A B and C we have activation transport and oxidation. So A in the cytosol fatty acids are activated by conversion into fatty eyl coa. Yes, this is true. It does it by consuming an A TP fatty acids activated by the carnitine are transported into the mitochondrial matrix. OK. By the mallet asperate show. No, it's done by the um carnitine show. So this is false. And so far this looks like our incorrect description. Fatty acids undergo beta oxidation in the mitochondrial matrix to produce acetyl coa multiple of them depending on the length of the fatty acid chain fa DH two and N A DH. This is true. The carnitine shuttle transport activated fatty acid from the cytosol to the mitochondrial matrix. This is true. So, out of all our statements, only option B is an incorrect one.
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Problem
Problem
Red blood cells do not have mitochondria. Can red blood cells use fatty acid oxidation to produce energy?
A
Yes
B
No
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Problem
Problem
For the biochemical pathways listed below, indicate which of the following energy carriers are produced in each: ATP (A), FADH2 (F), NADH (N), or none (X).
a) Glycolysis (_______)
b) β-Oxidation (_______)
c) Kreb’s cycle (_______)
d) Fatty acid activation (_______)
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