Write a short essay describing how epigenetic changes in cancer cells contribute to the development and maintenance of cancers.

Video transcript

Hi, everybody. Let's take a look at this practice problem together, abnormal regulation of which of the following enzyme classes has been associated with a variety of cancer subtypes. So recall that various self regulation abnormalities are associated with cancers. So, abnormal regulation of which enzyme is associated with cancer. And we've got the various options include a writer enzymes, be eraser enzymes, C reader enzymes or D all of the above. So we should note that all of these options, all of these enzymes modify or interact with his stones. Well, what are his stones? Recall that his stones affect chrome A tin structure because they are the proteins that add structural support for D N A in chroma tin. So let's go through our options. One by one for a writer enzymes. These add chemical groups onto the historians. Therefore, abnormal regulation of these enzymes can affect chroma tin remodeling and can be associated with cancer. So this is a possible answer choice. Then we've got B eraser enzymes, these remove chemical groups. So again, the removal of chemical groups, if there's abnormal regulation of this, this can also affect chroma tin structure and can also be associated with cancer. So this is also a potential answer option. Then we've got c reader enzymes. Now, reader enzymes interpret and recognize the changes of the addition or removal of chemical groups onto the his stones. Although they don't directly add or remove groups, they are important in chroma tin remodel. So they are also correct as well. Therefore, the correct answer is d all of the above writer eraser and reader enzymes have all been associated with cancer subtypes if there's abnormal regulation of them. Alright. Everybody, I hope you found this helpful and I'll see you soon for the next practice problem.