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Ch. 19 - Epigenetics
Chapter 18, Problem 5

Identical twins each carry the same genome, but over time, can develop different phenotypes. How can you explain this?

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span>Identical twins originate from a single fertilized egg, meaning they have the same genetic material or genome.</span
span>Despite having identical genomes, environmental factors can influence gene expression, leading to different phenotypes. This is known as epigenetics.</span
span>Epigenetic changes can occur due to various factors such as diet, stress, exposure to toxins, and lifestyle, which can modify how genes are turned on or off without changing the DNA sequence.</span
span>These epigenetic modifications can result in differences in physical appearance, behavior, and susceptibility to diseases between identical twins.</span
span>Additionally, random mutations and somatic changes that occur after the twins have developed from the single zygote can also contribute to phenotypic differences.</span

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Key Concepts

Here are the essential concepts you must grasp in order to answer the question correctly.

Genotype vs. Phenotype

The genotype refers to the genetic makeup of an organism, while the phenotype is the observable physical and physiological traits resulting from the interaction of the genotype with the environment. Identical twins share the same genotype, but differences in their phenotypes can arise due to environmental factors and individual experiences.
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Epigenetics

Epigenetics is the study of changes in gene expression that do not involve alterations to the underlying DNA sequence. Environmental influences, such as diet, stress, and exposure to toxins, can lead to epigenetic modifications that affect how genes are expressed, potentially resulting in different phenotypes in identical twins.
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Environmental Influences

Environmental influences encompass a wide range of factors, including lifestyle, nutrition, and social interactions, that can impact an individual's development and health. For identical twins, even slight differences in their environments can lead to variations in their phenotypes, despite having identical genetic information.
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