Describe how reversible chemical changes to DNA and histones are linked to chromatin modification.

Video transcript

Hi, everybody. Let's take a look at this practice problem together. Which of the following histone modification relaxes the grip of his stones on D N A thereby altering the structure of chroma tin. So recall that chroma tin is the condensed packed dense form of D N A and the his stones are bound together with the D N A to produce the chroma tin and his stones are proteins. So how do these histone proteins get modified? Is it a assimilation? Now, assimilation is the addition of an acetyl group which is COCH three. Is it modified through methylation or the addition of a methyl group Which is CH 3? Is it through phosphor relation? Which is the addition of phosphate, Which is P 04 or is the histone modified through D ubiquity nation? And ubiquity nation is the addition of the ubiquitous in protein. So you should recall that his stones get modified through a C dilation. Now, when they have the addition of a settle on them, it relaxes the D N A and this allows transcription factors to bind. So A is the correct answer. Alright, everybody, I hope you found this helpful and I'll see you soon for the next practice problem.