The process by which neutrophils squeeze through capillary walls in response to inflammatory signals is called:
a. Diapedesis
b. Chemotaxis
c. Margination
d. Opsonization

Verified step by step guidance

1. Step 1: Understand the key terms related to neutrophil movement during inflammation. Neutrophils are white blood cells that respond to infection or injury by moving from the bloodstream into the affected tissue.
2. Step 2: Define 'Diapedesis' as the process where neutrophils physically squeeze through the endothelial cells of capillary walls to exit the bloodstream and enter the tissue.
3. Step 3: Define 'Chemotaxis' as the directed movement of neutrophils toward chemical signals released at the site of inflammation.
4. Step 4: Define 'Margination' as the process where neutrophils move to the periphery of blood vessels and adhere to the endothelial lining in preparation for exiting the bloodstream.
5. Step 5: Define 'Opsonization' as the process where pathogens are marked for phagocytosis by neutrophils, enhancing their ability to recognize and engulf microbes.

Key Concepts

Diapedesis

Diapedesis is the process where neutrophils and other white blood cells move through the endothelial cells of capillary walls to reach sites of inflammation. This involves squeezing between endothelial cells without damaging the vessel, allowing immune cells to exit the bloodstream and enter tissues.

Chemotaxis

Chemotaxis refers to the directed movement of immune cells, like neutrophils, toward chemical signals released at sites of infection or injury. These chemical attractants guide the cells to the exact location where their defensive actions are needed.

Margination

Margination is the initial step in leukocyte migration where white blood cells move toward and adhere to the inner walls of blood vessels near the site of inflammation. This positioning facilitates their subsequent exit from the bloodstream during immune responses.