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Ch. 21 The Immune System: Innate and Adaptive Body Defenses
Chapter 20, Problem 3

Antibodies released by plasma cells are involved in a. humoral immunity, b. immediate hypersensitivity reactions, c. autoimmune disorders, d. all of the above.

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1
Understand that antibodies are proteins produced by plasma cells, which are derived from B cells.
Recognize that antibodies play a crucial role in humoral immunity by identifying and neutralizing pathogens like bacteria and viruses.
Consider that antibodies can also be involved in immediate hypersensitivity reactions, which are allergic responses that occur quickly after exposure to an allergen.
Acknowledge that in autoimmune disorders, antibodies may mistakenly target and attack the body's own tissues.
Evaluate each option to determine if antibodies are involved in all the listed processes: humoral immunity, immediate hypersensitivity reactions, and autoimmune disorders.

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Key Concepts

Here are the essential concepts you must grasp in order to answer the question correctly.

Humoral Immunity

Humoral immunity is a component of the adaptive immune system that involves the production of antibodies by plasma cells. These antibodies circulate in the bloodstream and bind to specific antigens, neutralizing pathogens or marking them for destruction by other immune cells. This type of immunity is crucial for defending against extracellular pathogens, such as bacteria and viruses.
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Immediate Hypersensitivity Reactions

Immediate hypersensitivity reactions, also known as allergic reactions, occur when the immune system overreacts to harmless substances, such as pollen or pet dander. In these reactions, antibodies, particularly IgE, bind to allergens and trigger the release of histamines and other chemicals from mast cells, leading to symptoms like itching, swelling, and difficulty breathing. Plasma cells play a role in producing these IgE antibodies.
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Autoimmune Disorders

Autoimmune disorders arise when the immune system mistakenly targets and attacks the body's own tissues, perceiving them as foreign. This can lead to chronic inflammation and damage to various organs. Antibodies produced by plasma cells can contribute to these disorders by binding to self-antigens, which can disrupt normal physiological functions and lead to conditions such as rheumatoid arthritis or lupus.
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