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Ch. 19 - Epigenetics

Chapter 18, Problem 23

Amino acids are classified as positively charged, negatively charged, or electrically neutral.

How does this property of lysine allow it to interact with DNA?

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Hello everyone and welcome to today's video. So the amino acid license interacts with D. N. A. Because of and so we're giving certain types of interactions that could be promoting this. Now remember that the side chain of license is going to be basic now because the side chain of license is basic and D. N. A. Has a negative charge is going to be able to interact with the false faith groups in the DNA molecule stabilizing it. And this is the nature of the interaction of license with the DNA molecule with the side chain of DNA. Now because of this, the basic nature of licensing is what it's going to be promoting the interaction of license and the DNA molecule. So the correct answer choice here is going to be answer choice. C. I really hope this video helped you and I hope to see you on the next one.
Related Practice
Textbook Question

From the data in Table 19.3, draw up a list of histone H3 modifications associated with gene activation. Then draw up a list of H3 modifications associated with repression.

Are these overlaps explained by different modifications?

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Textbook Question

From the data in Table 19.3, draw up a list of histone H3 modifications associated with gene activation. Then draw up a list of H3 modifications associated with repression.

If not, how can you reconcile these differences?

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Textbook Question

Amino acids are classified as positively charged, negatively charged, or electrically neutral.

Which category includes lysine?

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Textbook Question

Amino acids are classified as positively charged, negatively charged, or electrically neutral.

How does acetylation of lysine affect its interaction with DNA, and how is this related to the activation of gene expression?

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Textbook Question

A particular type of anemia in humans, called β-thalassemia, results from a severe reduction or absence of the normal β-globin chain of hemoglobin. However, the γ-globin chain, normally only expressed during fetal development, can functionally substitute for β-globin. A variety of studies have explored the use of the nucleoside 5-azacytidine for the expression of γ-globin in adult patients with β-thalassemia.

Explain why this drug may also have some adverse side effects.

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Textbook Question

A particular type of anemia in humans, called β-thalassemia, results from a severe reduction or absence of the normal β-globin chain of hemoglobin. However, the γ-globin chain, normally only expressed during fetal development, can functionally substitute for β-globin. A variety of studies have explored the use of the nucleoside 5-azacytidine for the expression of γ-globin in adult patients with β-thalassemia.

How might 5-azacytidine lead to expression of γ-globin in adult patients?

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