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Ch. 13 The Peripheral Nervous System and Reflex Activity
Marieb - Human Anatomy & Physiology 7th Edition
Marieb, Hoehn7th EditionHuman Anatomy & PhysiologyISBN: 9780805359091Not the one you use?Change textbook
Chapter 13, Problem 29

Compare and contrast flexor and crossed-extensor reflexes.

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Step 1: Define the flexor reflex. Explain that it is a protective, polysynaptic reflex that causes the withdrawal of a limb from a painful stimulus by activating flexor muscles and inhibiting extensor muscles on the same side of the body (ipsilateral response).
Step 2: Define the crossed-extensor reflex. Describe it as a complementary reflex that occurs simultaneously with the flexor reflex, involving the opposite limb (contralateral side). It activates extensor muscles and inhibits flexor muscles to support body weight when the other limb withdraws.
Step 3: Compare the pathways involved. Note that the flexor reflex involves sensory neurons synapsing with interneurons that excite ipsilateral flexor motor neurons and inhibit ipsilateral extensor motor neurons, while the crossed-extensor reflex involves interneurons crossing the spinal cord to excite contralateral extensor motor neurons and inhibit contralateral flexor motor neurons.
Step 4: Contrast their functional roles. Emphasize that the flexor reflex primarily serves to remove the limb from harm, whereas the crossed-extensor reflex helps maintain balance and posture by stabilizing the opposite limb.
Step 5: Summarize by highlighting that both reflexes work together during a painful stimulus to coordinate a rapid, protective response involving both limbs, ensuring withdrawal and postural support.

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Key Concepts

Here are the essential concepts you must grasp in order to answer the question correctly.

Flexor Reflex

The flexor reflex is a protective, withdrawal response that causes the contraction of flexor muscles to pull a limb away from a harmful stimulus. It is a polysynaptic reflex involving sensory neurons, interneurons, and motor neurons, primarily resulting in limb flexion to avoid injury.
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Flexor & Crossed-Extensor Reflexes

Crossed-Extensor Reflex

The crossed-extensor reflex complements the flexor reflex by extending the opposite limb to maintain balance when the other limb withdraws. It involves contralateral motor neurons activating extensor muscles, ensuring postural stability during the withdrawal response.
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Flexor & Crossed-Extensor Reflexes

Neural Pathways and Integration

Both reflexes involve complex neural circuits with sensory input, interneuronal processing, and motor output. The flexor reflex is ipsilateral, while the crossed-extensor reflex involves contralateral pathways, demonstrating how the spinal cord integrates signals to coordinate coordinated, bilateral motor responses.
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Alternative Pathway