Organic Chemistry
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Write a reasonable mechanism for the Birch reduction of acetophenone. Your mechanism should show the regiochemistry of the observed product.
What major product is expected from the reaction shown below?
Draw the plausible major product(s) of the reactions given below.
One synthetic method for producing N-methyl-1-phenylpropan-2-amine involves an interesting modification of the Birch Reduction process where, instead of reducing the aromatic ring, it eliminates the hydroxide ion (OH-) in pseudoephedrine. Propose a mechanism similar to the Birch reduction, explaining this unusual course.
Propose the mechanism of the Birch reduction of nitrobenzene. The reaction uses sodium in liquid ammonia and includes ethanol as a proton source. Show in the mechanism the observed preferred orientation in the reduction.
Propose the plausible structure of the product and the mechanism of its formation.