Organic Chemistry
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Propose a synthesis for the transformation below. Use whatever additional reagents that are needed.
Propose a method to accomplish the following synthetic conversion.
Draw the reaction of the preparation of 1-phenylhept-3-yn-2-ol using ethyne as the starting material.
Using acetylene as the starting material, show how each of the following compounds can be synthesized. In your synthesis, you can use any compounds with four or less carbon atoms.(i) propanal(ii) acetone(iii) (±) 2,3-dibromobutane
Determine how to prepare the given organic molecule using acetylene as the starting material.
Determine the steps and the reagents needed for the following transformation.
Provide the alkyne and the alkyl halide used for synthesizing the alkyne below. [There are two possible answers.]
Repeating same series of steps is done when performing synthesis analysis to produce the desired product. To see this in action, the alkynide synthesis below determines how the following aldehyde is created, starting with a terminal alkene of five carbons. Is the synthesis correct?
Give the synthesis of the product shown using the provided reactant, any inorganic reagents, and any organic molecule with less than four carbons.
Give the reaction sequence showing how the following product can be prepared from the starting material.
Draw the products that will form when the compounds below react with CH3CH2CH2CH2C≡C:–Na+ followed by H2O workup.
(i) cyclopentanone
(ii) CH3CH2CHO
The addition of an acetylide ion to a carbonyl group is used in the synthesis of 3-ethynylhept-1-en-3-ol. Propose a synthesis using acetylene and a carbonyl compound as the starting materials. (Ignore stereochemistry)
Using acetylene as the starting material, show the synthesis of 6,6-dimethyl-1-heptyn-3-ol.
Propose the synthesis of the given compound starting from acetylene.
Explain the reason why the reaction of an epoxide given below with an acetylide will not form the target molecule, and determine the side reaction that occurs instead.
Using the starting material below, propose the synthesis of the product using 3 steps.
Note: While multiple approaches may exist to achieve each synthesis, the minimum steps required are indicated above each reaction arrow.
Propose a synthesis of the molecule on the right, starting with the molecule on the left. Although there may be other synthetic routes that are worthwhile, the ideal number of steps is indicated over the reaction arrow.
How can the compound below be produced from an organic molecule with no more than three carbons?
Outline the synthesis of the given compound starting with an organic structure with three carbons or fewer.
Design a multistep synthesis to show how the following target molecule can be produced using the given starting material.
Write a possible reaction sequence to synthesize the following aldehyde from the given alkyl halide.
Provide the synthesis of pentan-2-one using propyne, any inorganic reagents, and any organic compounds with fewer than four carbons.
Describe the steps required to make hexan-3-ol using but-1-yne, any inorganic reagents, and any organic molecule with less than four carbons.
Write the synthesis of the following compound from the provided starting material. Include the structures of the intermediate products.
How would you synthesize the following compound starting from ethyne and any other required substance?
3-methylpent-1-yn-3-ol
hepta-1,6-diyne-3,5-diol
How would you synthesize 1-phenylbut-2-yn-1-ol starting from benzaldehyde and any other required reagents?
Fill in the missing reagents to complete the synthesis.
Using the given initial compound, synthesize the molecule shown on the right using the minimum number of steps necessary as indicated. Note: The aldehyde is made in the reaction.