Mark each statement as either true or false. Rewrite false statements to make them true by changing the underlined words.

__________ MHC class II molecules are found on T cells.

Verified step by step guidance

1. Identify the statement to be evaluated: 'MHC class II molecules are found on T cells.'
2. Recall the function and location of MHC class II molecules. They are primarily expressed on antigen-presenting cells (APCs) such as dendritic cells, macrophages, and B cells.
3. Understand that T cells, specifically CD4+ T helper cells, interact with MHC class II molecules but do not express them.
4. Determine the truth value of the statement: Since MHC class II molecules are not found on T cells, the statement is false.
5. Rewrite the false statement to make it true: 'MHC class II molecules are found on antigen-presenting cells such as dendritic cells, macrophages, and B cells.'

Key Concepts

MHC Class II Molecules

Major Histocompatibility Complex (MHC) class II molecules are proteins found primarily on the surface of certain immune cells, such as B cells, dendritic cells, and macrophages. They play a crucial role in the immune response by presenting antigens to CD4+ T helper cells, which are essential for orchestrating the adaptive immune response.

T Cells

T cells are a type of white blood cell that plays a central role in the immune response. They are primarily involved in recognizing and responding to specific antigens. There are different types of T cells, including CD4+ T helper cells, which interact with MHC class II molecules, and CD8+ cytotoxic T cells, which interact with MHC class I molecules.

Antigen Presentation

Antigen presentation is the process by which immune cells display antigens on their surface using MHC molecules. This is critical for T cell activation, as T cells recognize these presented antigens through their T cell receptors (TCRs). MHC class II molecules specifically present extracellular antigens to CD4+ T cells, facilitating a targeted immune response.