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Ch. 5 - Chromosome Mapping in Eukaryotes
Chapter 5, Problem 4

Why does more crossing over occur between two distantly linked genes than between two genes that are very close together on the same chromosome?

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Understand that crossing over is a process during meiosis where homologous chromosomes exchange segments of genetic material.
Recognize that the likelihood of crossing over between two genes is related to the physical distance between them on a chromosome.
Recall that genes that are far apart on a chromosome have a higher probability of crossing over because there is more space for the crossover event to occur.
Consider that genes that are very close together are less likely to be separated by crossing over, as there is less physical distance for the crossover to take place.
Conclude that more crossing over occurs between distantly linked genes because the greater distance increases the chance of a crossover event happening between them.

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Key Concepts

Here are the essential concepts you must grasp in order to answer the question correctly.

Crossing Over

Crossing over is a genetic process that occurs during meiosis, where homologous chromosomes exchange segments of genetic material. This exchange increases genetic diversity in gametes. The frequency of crossing over between two genes is influenced by their physical distance on the chromosome; genes that are farther apart are more likely to undergo crossing over.
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Genetic Linkage

Genetic linkage refers to the tendency of genes located close to each other on the same chromosome to be inherited together. When genes are closely linked, the likelihood of crossing over occurring between them is reduced, leading to less genetic variation. Conversely, distantly linked genes have a higher chance of being separated during crossing over.
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Recombination Frequency

Recombination frequency is a measure of how often crossing over occurs between two genes during meiosis. It is expressed as a percentage and is directly related to the physical distance between genes on a chromosome. A higher recombination frequency indicates that genes are farther apart, while a lower frequency suggests they are closer together, affecting their inheritance patterns.
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