Ch. 5 - Chromosome Mapping in Eukaryotes
Chapter 5, Problem 23
Based on our discussion of the potential inaccuracy of mapping (see Figure 5.12), would you revise your answer to Problem 22? If so, how?
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Related Practice
Textbook Question
An organism of the genotype AaBbCc was testcrossed to a triply recessive organism (aabbcc). The genotypes of the progeny are presented in the following table.
20 AaBbCc 20 AaBbcc
20 aabbCc 20 aabbcc
5 AabbCc 5 Aabbcc
5 aaBbCc 5 aaBbcc
If these three genes were all assorting independently, how many genotypic and phenotypic classes would result in the offspring, and in what proportion, assuming simple dominance and recessiveness in each gene pair?
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Textbook Question
An organism of the genotype AaBbCc was testcrossed to a triply recessive organism (aabbcc). The genotypes of the progeny are presented in the following table.
20 AaBbCc 20 AaBbcc
20 aabbCc 20 aabbcc
5 AabbCc 5 Aabbcc
5 aaBbCc 5 aaBbcc
Answer part (a) again, assuming the three genes are so tightly linked on a single chromosome that no crossover gametes were recovered in the sample of offspring.
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Textbook Question
An organism of the genotype AaBbCc was testcrossed to a triply recessive organism (aabbcc). The genotypes of the progeny are presented in the following table.
20 AaBbCc 20 AaBbcc
20 aabbCc 20 aabbcc
5 AabbCc 5 Aabbcc
5 aaBbCc 5 aaBbcc
What can you conclude from the actual data about the location of the three genes in relation to one another?
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Textbook Question
How do we know that in humans the X chromosomes play no role in human sex determination, while the Y chromosome causes maleness and its absence causes femaleness?
Why are many expected crossover phenotypes missing? Can any of these loci be mapped from the data given here? If so, determine map distances.
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Textbook Question
Traditional gene mapping has been applied successfully to a variety of organisms including yeast, fungi, maize, and Drosophila. However, human gene mapping has only recently shared a similar spotlight. What factors have delayed the application of traditional gene-mapping techniques in humans?
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Textbook Question
In a certain plant, fruit is either red or yellow, and fruit shape is either oval or long. Red and oval are the dominant traits. Two plants, both heterozygous for these traits, were testcrossed, with the following results.
Determine the location of the genes relative to one another and the genotypes of the two parental plants.
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