Ch. 5 - Chromosome Mapping in Eukaryotes
Chapter 5, Problem 22
An organism of the genotype AaBbCc was testcrossed to a triply recessive organism (aabbcc). The genotypes of the progeny are presented in the following table. 20 AaBbCc 20 AaBbcc 20 aabbCc 20 aabbcc 5 AabbCc 5 Aabbcc 5 aaBbCc 5 aaBbcc Answer part (a) again, assuming the three genes are so tightly linked on a single chromosome that no crossover gametes were recovered in the sample of offspring.
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Textbook Question
Are mitotic recombinations and sister chromatid exchanges effective in producing genetic variability in an individual? in the offspring of individuals?
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Textbook Question
What possible conclusions can be drawn from the observations that in male Drosophila, no crossing over occurs, and that during meiosis, synaptonemal complexes are not seen in males but are observed in females where crossing over occurs?
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Textbook Question
An organism of the genotype AaBbCc was testcrossed to a triply recessive organism (aabbcc). The genotypes of the progeny are presented in the following table.
20 AaBbCc 20 AaBbcc
20 aabbCc 20 aabbcc
5 AabbCc 5 Aabbcc
5 aaBbCc 5 aaBbcc
If these three genes were all assorting independently, how many genotypic and phenotypic classes would result in the offspring, and in what proportion, assuming simple dominance and recessiveness in each gene pair?
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Textbook Question
An organism of the genotype AaBbCc was testcrossed to a triply recessive organism (aabbcc). The genotypes of the progeny are presented in the following table.
20 AaBbCc 20 AaBbcc
20 aabbCc 20 aabbcc
5 AabbCc 5 Aabbcc
5 aaBbCc 5 aaBbcc
What can you conclude from the actual data about the location of the three genes in relation to one another?
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Textbook Question
Based on our discussion of the potential inaccuracy of mapping (see Figure 5.12), would you revise your answer to Problem 22? If so, how?
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Textbook Question
How do we know that in humans the X chromosomes play no role in human sex determination, while the Y chromosome causes maleness and its absence causes femaleness?
Why are many expected crossover phenotypes missing? Can any of these loci be mapped from the data given here? If so, determine map distances.
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