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Ch. 15 - Gene Mutation, DNA Repair, and Transposition

Chapter 15, Problem 1

In this chapter, we focused on how gene mutations arise and how cells repair DNA damage. At the same time, we found opportunities to consider the methods and reasoning by which much of this information was acquired. From the explanations given in the chapter, How do we know that DNA repair mechanisms detect and correct the majority of spontaneous and induced mutations?

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Hey everyone. Let's take a look at this question together. What makes it a challenge for scientists to study mutations through spontaneous mutations? Let's recall what we've learned about what spontaneous mutations are to figure out why it is a challenge for the scientists to study mutations. By using that though, we know that spontaneous mutations are unpredictable as well as infrequent. And we do not know their causal factors, meaning that they occur without any human interference. And they can be influenced by many environmental factors like radiation chemicals or anything else. So we do not know what causes those spontaneous mutations, which them being unpredictable, infrequent and unknown are many challenges that scientists have to go through in order to study mutations through spontaneous mutations. So, answer choice D. Is the correct answer, because they have an unpredictable nature. They are infrequent and their causal factors are unclear because we do not know what influences them to occur. And so answer choice D. All options are correct is the best answer here. I hope you found this video to be helpful. Thank you and goodbye.
Related Practice
Textbook Question

In this chapter, we focused on how gene mutations arise and how cells repair DNA damage. At the same time, we found opportunities to consider the methods and reasoning by which much of this information was acquired. From the explanations given in the chapter,

How do we know that mutations occur randomly?

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Textbook Question
In this chapter, we focused on how gene mutations arise and how cells repair DNA damage. At the same time, we found opportunities to consider the methods and reasoning by which much of this information was acquired. From the explanations given in the chapter, How do we know that certain chemicals and wavelengths of radiation induce mutations in DNA?
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Textbook Question
Write a short essay contrasting how these concepts may differ between bacteria and eukaryotes.
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Textbook Question

Price et al. [(1999). J. Bacteriol. 181:2358–2362] conducted a genetic study of the toxin transport protein (PA) of Bacillus anthracis, the bacterium that causes anthrax in humans. Within the 2294-nucleotide gene in 26 strains they identified five point mutations—two missense and three synonyms—among different isolates. Necropsy samples from an anthrax outbreak in 1979 revealed a novel missense mutation and five unique nucleotide changes among ten victims. The authors concluded that these data indicate little or no horizontal transfer between different B. anthracis strains.

Which types of nucleotide changes (missense or synonyms) cause amino acid changes?

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Textbook Question

Price et al. [(1999). J. Bacteriol. 181:2358–2362] conducted a genetic study of the toxin transport protein (PA) of Bacillus anthracis, the bacterium that causes anthrax in humans. Within the 2294-nucleotide gene in 26 strains they identified five point mutations—two missense and three synonyms—among different isolates. Necropsy samples from an anthrax outbreak in 1979 revealed a novel missense mutation and five unique nucleotide changes among ten victims. The authors concluded that these data indicate little or no horizontal transfer between different B. anthracis strains.

On what basis did the authors conclude that evidence of horizontal transfer is absent from their data?

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