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Ch. 15 - Gene Mutation, DNA Repair, and Transposition

Chapter 15, Problem 9

Describe a tautomeric shift and how it may lead to a mutation.

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Hey everyone. Let's take a look at this question together. After a todd americ shift. Inthe I mean it pairs with what? So let's recall what we know about the makeup of time. I mean after that todd americ shift to figure out which base it pairs with. So what do we mean by that Todd americ shift in timing? So we know that when targu mures are used we end up with bases with different proton positions meaning that after that todd americ shift for example with I mean the proton is in a different position than it was before. So let's take a look at it. I mean in it's normal keto form and then let's take a look at Simon in that rare Enel form which is after that taught americ shift. And so here we can see timing in that normal keto form. And here we can see timing in that rare in all form. And so in the normal form we can see that it pairs with and in in because of that proton configuration. However when it's in that rare Enel form because of that change in the proton position timing pairs with guanine. And so we can say that after that todd americ shift in time in time in pairs with guanine or answer choice B. The correct answer because we know that that todd americ shift in timing changes that proton position so that it goes from pairing with adenine to being paired with guanine. So answer choice B. Is the correct answer. I hope you found this video to be helpful. Thank you and goodbye