Ch. 15 - Gene Mutation, DNA Repair, and Transposition
Chapter 15, Problem 9
Describe a tautomeric shift and how it may lead to a mutation.
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Related Practice
Textbook Question
Most mutations in a diploid organism are recessive. Why?
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Textbook Question
What is the difference between a silent mutation and a neutral mutation?
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Textbook Question
When the amino acid sequences of insulin isolated from different organisms were determined, differences were noted. For example, alanine was substituted for threonine, serine for glycine, and valine for isoleucine at corresponding positions in the protein. List the single-base changes that could occur in codons of the genetic code to produce these amino acid changes.
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Textbook Question
In studies of the amino acid sequence of wild-type and mutant forms of tryptophan synthetase in E. coli, the following changes have been observed:
Determine a set of triplet codes in which only a single-nucleotide change produces each amino acid change.
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Textbook Question
Contrast and compare the mutagenic effects of deaminating agents, alkylating agents, and base analogs.
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Textbook Question
Why are frameshift mutations likely to be more detrimental than point mutations, in which a single pyrimidine or purine has been substituted?
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