While much remains to be learned about the role of nucleosomes and chromatin structure and function, recent research indicates that in vivo chemical modification of histones is associated with changes in gene activity. One study determined that acetylation of H3 and H4 is associated with 21.1 percent and 13.8 percent increases in yeast gene activity, respectively, and that histones associated with yeast heterochromatin are hypomethylated relative to the genome average [Bernstein et al. (2000)]. Speculate on the significance of these findings in terms of nucleosome–DNA interactions and gene activity.

Video transcript

Hey, everyone, let's take a look at this question together, the less condensed form of chromatin is called what? And the highly condensed form of chromatin is referred to as the blank. So let's recall what we know about chromatin to try to figure out what the less condensed form is called and what the highly condensed form is called. So we know that we have chromatin, which is the material that our chromosomes are composed of. And so we have two different types of chromatin. So we have U chromatin and we also have heterochromatin. And so talking about e chromatin first, we know that it is the less condensed form of chrome. And we also know that it is used to be transcribed into RN A. And on the other hand, heterochromatin is the highly condensed form. So it is highly condensed and it is actually not used to be transcribed into that RN A. And so looking at what we've just written down about the two forms of chromatin, we know that E chromatin is less condensed and heterochromatin is highly condensed. So that means that the less condensed form of chromatin is called U chromatin in the highly condensed form of chromatin is that hetero chromatin. So looking at our answer choices, which one best represents what we have written in the question. And that would be answer choice B the correct answer because we know that the less condensed form of chromatin is called U chromatin. And the highly condensed form of chromatin is referred to as the heterochromatin, which is answer choice B the correct answer. I hope you found this video to be helpful. Thank you and goodbye.