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Ch. 11 - DNA Replication and Recombination

Chapter 11, Problem 13

List and describe the function of the ten subunits constituting DNA polymerase III. Distinguish between the holoenzyme and the core enzyme.

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Hello, everyone. Welcome back. Here's our next question which of the following sentences is false regarding DNA polymerase three, holoenzyme. And our answer choices are a, it interacts with the DNA helicase through the Tau subunit, which also binds to the DNA polymerase Choice B during bacterial chromosome DNA replication. It is responsible for initiating the elongation of DNA chains. Choice C. This enzyme only plays a major role in DNA repair and choice D both B and C. So we're looking for the false statement about DNA polymerase three and we have to keep in mind that we have that answer choice both B and C. So we might have more than one false statement. So with that in mind, let's look through our answer choices. Well, A says that it interacts with DNA helicase through the tau subunit which also binds the DNA polymerase. Well, this is a true statement. So a little red tea. So it would not be our answer choice since we're looking for a false answer. So let's look at choice B during bacterial chromosome during bacterial chromosomal DNA replication. It is responsible for initiating the elongation of DNA chains. Well, this is also true DNA plum rice three is the main enzyme involved in the replication of DNA and works by elongating the DNA chain, adding the new base pairs to make it longer. So that's true. And therefore choice B is not our answer. We can then also eliminate choice D both B and C since B is not correct or since B is not our answer because it is true. And then finally, choice C, this enzyme only plays a major role in DNA repair. Well, this isn't our false statement. Its major role is in DNA replication, not repair. So this is a false statement and therefore it is the answer we're looking for. So again, which of the following sentences is false. Regarding DNA polymerase 3 Holoenzyme to ac, this enzyme only plays a major role in DNA repair. See you in the next video.