Ch. 11 - DNA Replication and Recombination
Chapter 11, Problem 1
In this chapter, we focused on how DNA is replicated and synthesized. We also discussed recombination at the DNA level. Along the way, we encountered many opportunities to consider how this information was acquired. On the basis of these discussions, what answers would you propose to the following fundamental questions? What is the experimental basis for concluding that DNA replicates semiconservatively in both bacteria and eukaryotes?
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Textbook Question
In this chapter, we focused on how DNA is replicated and synthesized. We also discussed recombination at the DNA level. Along the way, we encountered many opportunities to consider how this information was acquired. On the basis of these discussions, what answers would you propose to the following fundamental questions?
How do we know that in vivo DNA synthesis occurs in the 5' to 3' direction?
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Textbook Question
In this chapter, we focused on how DNA is replicated and synthesized. We also discussed recombination at the DNA level. Along the way, we encountered many opportunities to consider how this information was acquired. On the basis of these discussions, what answers would you propose to the following fundamental questions?
How do we know that DNA synthesis is discontinuous on one of the two template strands?
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Textbook Question
What observations reveal that a 'telomere problem' exists during eukaryotic DNA replication, and how did we learn of the solution to this problem?
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Textbook Question
In this chapter, we focused on how DNA is organized at the chromosomal level. Along the way, we found many opportunities to consider the methods and reasoning by which much of this information was acquired. From the explanations given in the chapter, what answers would you propose to the following fundamental questions:
How do we know that satellite DNA consists of repetitive sequences and has been derived from regions of the centromere?
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Textbook Question
Write a short essay that distinguishes between the terms replication and synthesis, as applied to DNA. Which of the two is most closely allied with the field of biochemistry?
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Textbook Question
Compare conservative, semiconservative, and dispersive modes of DNA replication.
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