Ch. 10 - DNA Structure and Analysis
Chapter 10, Problem 13
Draw the chemical structure of a dinucleotide composed of A and G. Opposite this structure, draw the dinucleotide composed of T and C in an antiparallel (or upside-down) fashion. Form the possible hydrogen bonds.
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Textbook Question
How are the carbon and nitrogen atoms of the sugars, purines, and pyrimidines numbered?
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Adenine may also be named 6-amino purine. How would you name the other four nitrogenous bases, using this alternative system? (O is indicated by 'oxy-,' and CH₃ by 'methyl.')
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Textbook Question
Human adult hemoglobin is a tetramer containing two alpha (α) and two beta (β) polypeptide chains. The α gene cluster on chromosome 16 and the β gene cluster on chromosome 11 share amino acid similarities such that 61 of the amino acids of the α-globin polypeptide (141 amino acids long) are shared in identical sequence with the β-globin polypeptide (146 amino acids long). How might one explain the existence of two polypeptides with partially shared function and structure on two different chromosomes?
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Textbook Question
Describe the various characteristics of the Watson–Crick double-helix model for DNA.
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Textbook Question
What evidence did Watson and Crick have at their disposal in 1953? What was their approach in arriving at the structure of DNA?
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Textbook Question
What might Watson and Crick have concluded had Chargaff's data from a single source indicated the following?
A T G C
% 29 19 21 31
Why would this conclusion be contradictory to Wilkins's and Franklin's data?
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