Write a short essay describing how cis-acting regulatory elements...

Question

Write a short essay describing how cis-acting regulatory elements, activators, and chromatin modifiers are all coordinately involved in regulating transcription initiation.

Accepted Answer

Hi everyone. Let's take a look at this practice problem together. This regulatory elements are non coding regions of DNA that participate in the transcription process. How do they regulate the transcription of the neighboring genes. Okay so the prefix cysts it literally means on the same side. So cis regulatory elements are on the same chromosome as the genes that they regulate. And now they can regulate the gene transcription by increasing it or by decreasing it. But how do they do this? Is it a they produce transcription factors? Well remember they are non coding. So non coding is that they're not going to produce anything. They're not gonna code for anything. So A. Is not correct is it? See that they bind with the RNA. Preliminaries? Now transcription factors are wet bind with RNA preliminaries and recall that that's needed in order for the preliminaries to attach to D. N. A. For transcription to occur. So this is not the correct answer either is it D they release activator proteins. Now recall that activators increase transcription so this increases transcription. And so if we released them that would cause the decrease of transcription. And if that was their only function that only describes half of what this regulatory elements do since they should be able to up regulate or deregulate transcription. And so our answer cannot be D either Our answer is B. They bind with the transcription factors and this is how they regulate transcription. They bind to the transcription factors. And then through several processes they can then increase or decrease transcription of the genes. So this is our answer. Alright, everyone. I hope you found this helpful, and I'll see you soon for the next practice problem.

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Write a short essay describing how cis-acting regulatory elements, activators, and chromatin modifiers are all coordinately involved in regulating transcription initiation.