Which of the following correctly describe an exergonic reaction? Select True or False for each statement. T/F The products have lower Gibbs free energy than the reactants. T/F Activation energy is required for the reaction to proceed. T/F The products always have lower entropy than the reactants. T/F The reaction always occurs quickly.

What is a transition state? a. the shape adopted by an enzyme that has an inhibitory molecule bound at its active site b. the amount of kinetic energy required for a reaction to proceed c. the intermediate complex formed as covalent bonds in the reactants are being broken and re-formed during a reaction d. the enzyme shape after binding an allosteric regulatory molecule

How does pH affect enzyme-catalyzed reactions? a. Protons serve as substrates for most reactions. b. Energy stored in protons is used to drive endergonic reactions. c. Proton concentration increases the kinetic energy of the reactants, enabling them to reach their transition state. d. The concentration of protons affects an enzyme's folded structure and reactivity.

What factors determine whether a chemical reaction is spontaneous or not?

Which of the following correctly describe an active site? Select True or False for each statement. T/F It is the location in an enzyme where substrates bind. T/F It is the place where a molecule or ion binds to an inactive enzyme to induce a shape change to make it active. T/F It is the portion of an enzyme where chaperones bind to help enzymes fold. T/F It is the site on an enzyme where catalysis occurs.

Explain the lock-and-key model of enzyme activity. What is incorrect about this model?

If you were to expose glucose to oxygen on your lab bench, why would you not expect to see it burn as described by the reaction in Figure 8.6? a. The reaction is endergonic and requires an input of energy. b.The reaction is not spontaneous unless an enzyme is added. c. The sugar must first be phosphorylated to increase its potential energy. d. Activation energy is required for the sugar and oxygen to reach their transition state.

In Figure 8.10, the energetic coupling of substrate phosphorylation and an endergonic reaction are shown. If the hydrolysis of ATP releases 7.3 kcal of free energy, use the graph in this figure to estimate what you would expect the ∆G values to be for the uncoupled reaction and the two steps in the coupled reaction.

You have discovered an enzyme that appears to function only when a particular sugar accumulates. Which of the following scenarios would you predict to be responsible for activating this enzyme? a. The sugar cleaves the enzyme to form the active conformation. b. The sugar is an allosteric regulatory molecule for the enzyme. c. The sugar is a competitive inhibitor for the enzyme. d. The sugar phosphorylates the enzyme to form the active conformation