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Ch. 8 - Energy and Enzymes: An Introduction to Metabolism

Chapter 8, Problem 3

How does pH affect enzyme-catalyzed reactions? a. Protons serve as substrates for most reactions. b. Energy stored in protons is used to drive endergonic reactions. c. Proton concentration increases the kinetic energy of the reactants, enabling them to reach their transition state. d. The concentration of protons affects an enzyme's folded structure and reactivity.

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Hi everyone. Let's look at our next problem. It says which of the following factors affect activity of an enzyme. And when I look at my answer choices, I want to notice that choice D. Is all of the above. So there's a possibility that all three of these could be correct. So let's look at choice A. It says P. H. Well every enzyme has an optimal ph where it operates best. So outside of the optimal range that will decrease enzyme activity. So ph definitely affects the activity of the enzyme. And in fact extreme ph values well, completely denatured the enzyme. So ph definitely has an effect. So just put a little dot here, since we know we can have more than one correct answer. Choice B says temperature. Um In general an increase in temperature will cause an increase in enzyme activity and the rate of the reaction. However, just like with ph extreme temperature can halt the activity. Either extreme heat denatured the enzyme or extreme cold. Um This molecule is not moving around the enzyme won't be able to do what it needs to do and you'll halt um the activity of the enzyme. So temperature definitely affects activity and enzyme. And finally, choice C inhibitor. Well, an inhibitor um blocks the active side of the enzyme and this will slow down or stop enzyme activity by preventing the reactivates coming into the active site. So inhibitor definitely affects enzyme activity. So, since all three of these factors can affect the activity of an enzyme are correct answer is choice D. All of the above. Hope that helps you in the next video.