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Ch. 8 - Energy and Enzymes: An Introduction to Metabolism

Chapter 8, Problem 4

Which of the following correctly describe an active site? Select True or False for each statement. T/F It is the location in an enzyme where substrates bind. T/F It is the place where a molecule or ion binds to an inactive enzyme to induce a shape change to make it active. T/F It is the portion of an enzyme where chaperones bind to help enzymes fold. T/F It is the site on an enzyme where catalysis occurs.

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Welcome back. Here's our next problem. It says the active site is the specific region in a blank where a blank binds. Well, this is pretty straightforward when we think about active site. Um hopefully that triggers our memory. To think about an enzyme. Uh The characteristic of an enzyme is that it has this region called an active site. Oh where the and the word we were looking for is substrate. Substrate here comes along and binds to the active site of the enzyme. That's what allows the enzyme to catalyze the reaction in which the substrate is going to participate. So we want to look for enzyme in our first slot here and substrate in our second. So let's look at our answer choices knowing we need enzyme in the first slot. So we can eliminate choice A. Because that has substrate first choice B has enzyme first. So that's a possible answer. Choice C. Has enzyme first choice D. Has the word product first. So we can eliminate that. And then our second word should be substrate. So choice B does have substrate as the second term. So choice B will be correct. Choice C though has product is the second word. That's not a correct answer. Of course the product of the reaction is what happens after the substrate binds the end time undergoes whatever chemical reactions can undergo. And then the product is made. So the active site is the specific region in a an choice B enzyme where a substrate binds. See you in the next video
Related Practice
Textbook Question

What is a transition state? a. the shape adopted by an enzyme that has an inhibitory molecule bound at its active site b. the amount of kinetic energy required for a reaction to proceed c. the intermediate complex formed as covalent bonds in the reactants are being broken and re-formed during a reaction d. the enzyme shape after binding an allosteric regulatory molecule

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Textbook Question

How does pH affect enzyme-catalyzed reactions? a. Protons serve as substrates for most reactions. b. Energy stored in protons is used to drive endergonic reactions. c. Proton concentration increases the kinetic energy of the reactants, enabling them to reach their transition state. d. The concentration of protons affects an enzyme's folded structure and reactivity.

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Textbook Question

What factors determine whether a chemical reaction is spontaneous or not?

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Textbook Question

Explain the lock-and-key model of enzyme activity. What is incorrect about this model?

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Textbook Question

If you were to expose glucose to oxygen on your lab bench, why would you not expect to see it burn as described by the reaction in Figure 8.6? a. The reaction is endergonic and requires an input of energy. b.The reaction is not spontaneous unless an enzyme is added. c. The sugar must first be phosphorylated to increase its potential energy. d. Activation energy is required for the sugar and oxygen to reach their transition state.

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Textbook Question

In Figure 8.10, the energetic coupling of substrate phosphorylation and an endergonic reaction are shown. If the hydrolysis of ATP releases 7.3 kcal of free energy, use the graph in this figure to estimate what you would expect the ∆G values to be for the uncoupled reaction and the two steps in the coupled reaction.

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