What does it mean to say that a signal is transduced? a. The signaling molecule enters the cell directly and elicits a cellular response. b. The signal is generated by the production of proteins. c. The physical form of the signal changes between the outside of the cell and the inside. d. The signal is amplified.
Ch. 11 - Cell-Cell Interactions
Chapter 11, Problem 3
Which of the following actions correctly describe a role performed by at least one type of intercellular connection? Select True or False for each statement. T/F Allows communication between adjacent cells. T/F Forms a watertight barrier between the cells. T/F Uses components of the extracellular matrix to indirectly connect adjacent cells. T/F Associates with cytoskeletal components to resist pulling forces.

1
True - Gap junctions allow communication between adjacent cells by permitting the passage of ions and small molecules, facilitating intercellular communication.
True - Tight junctions form a watertight barrier between cells, preventing the passage of molecules and ions through the space between cells.
False - Intercellular connections such as gap junctions, tight junctions, and desmosomes directly connect cells rather than using components of the extracellular matrix.
True - Desmosomes are specialized structures that connect to intermediate filaments of the cytoskeleton, providing mechanical strength to tissues by resisting pulling forces.

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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Intercellular Connections
Intercellular connections are structures that facilitate communication and adhesion between adjacent cells. They include tight junctions, gap junctions, and desmosomes, each serving distinct functions such as forming barriers, allowing ion and molecule passage, and providing mechanical strength.
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Tight Junctions
Tight junctions are specialized connections that create a watertight seal between adjacent cells, preventing the passage of substances through the intercellular space. They are crucial in epithelial tissues, where they maintain distinct apical and basolateral surfaces, thus regulating permeability.
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Gap Junctions
Gap junctions are intercellular channels that allow direct communication between adjacent cells by permitting the passage of ions and small molecules. They play a vital role in coordinating cellular activities, such as in cardiac muscle cells, where they facilitate synchronized contractions.
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Related Practice
Textbook Question
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Textbook Question
Summarize the experimental evidence in sponges showing that animal cells adhere to each other selectively. Explain the molecular basis of selective adhesion.
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Textbook Question
Suppose you were to model amplification by the phosphorylation cascade in Figure 11.16, using a penny for each kinase 1, a nickel for each kinase 2, and a dime for each kinase 3. Also suppose that Ras and each of the kinases can activate 10 proteins. How much money would you need to construct your model?
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