Oxidative Phosphorylation - Video Tutorials & Practice Problems
On a tight schedule?
Get a 10 bullets summary of the topic
1
concept
Oxidative Phosphorylation Concept 1
Video duration:
2m
Play a video:
Now oxidated phosphorylation is the synthesis of a TP from AD P. Here it uses potential energy stored in the proton gradient built by the electron transport chain or etc here we have chem osmosis. This is just the diffusion of ions across a membrane down their concentration gradient. And here remember osmosis is the movement from a higher concentration to a lower concentration in this sense. If we take a look here, we have our electron transport chain. Remember the electron transport chain uses complexes 1 to 4 N A DH drops off electrons at complex one fa DH two drops them off at complex two. We're gonna say here, Coenzyme Q helps to shuttle those electrons to complex three. And then cytochrome c will help to shuttle those electrons to complex four. We're gonna have protons being pumped into the inter membrane space in complexes 13 and four. This is gonna cause a gradient to be formed. This is gonna help electrons to move down the line with the movement of these protons 802 would act as the final electronic sector generating water. Now, on the other side of this, we go to yet another complex complex fine, also called a TP synthese. What happens here is that protons then move back into the matrix. And we're going to say as it does this, we're going to phosphate AD P. So, ad P is going to gain an inorganic phosphate to become a TP. And this is where oxidative phosphorylation occurs. Now, here we're gonna say that a TP synthese or complex five, this is just your enzyme complex that facilitates hem osmosis and synthesizes a TP. We're gonna say here that proton diffusion through a TP synthese releases releases energy that drives ad P phosphorylation. So all of this taking of electrons shuttling them over to the electron transport chain. The whole payoff was getting us to complex five where A TP syntax comes into play and we start generating a lot of A TPS. Now, how much A TP could we generate? We'll find out in the next video.
2
concept
Oxidative Phosphorylation Concept 2
Video duration:
51s
Play a video:
Now the total amount of A TP produced by oxidative phosphorylation. Remember we make six N A DH S and two FA DH two for two cycles of the TC A. And we're gonna say here N A DH, we have 2.5 A TP per one, N A DH. And we have 1.5 A TP for one FA DH two. Now we're gonna say six times 2.5 gives me 15, two times, 1.5 gives me three. This gives me a theoretical 18 A TP molecules theoretical because that's why we have disasters here. Our number may be a little bit higher or a bit lower based on situations. OK. So here we have to say 18 is the most realistic number in terms of the amount of A TP that we can generate through oxidative phosphorylation.
3
example
Oxidative Phosphorylation Example 1
Video duration:
1m
Play a video:
The diffusion of H plus ions from higher concentration to lower concentration A occurs at ad P synthese complex. Now, here it's going on from complex one all the way to complex five. And also it's a TP synthese not ad P. Next requires energy supplied by the formation of a TP. Here, this diffusion is a natural thing moving from an area of high concentration to an area of low concentration. We have electrons traveling along the way between the different complexes kind of shuttling this whole thing along. So no energy is required driven by a TP synthesis. No, the we're gonna use the natural diffusion harness that in order to pump H plus ions back into the matrix and thereby make a TP. Here D provides energy that facilitates oxidative phosphorylation of AD P. Yes. So H plus ions are building up in the inter membrane space. And we're gonna say as we're diffusing, going from complex one all the way to complex five, they're actually going to be pumped back into the matrix at complex five, which is our A TP synthese. We're gonna use this pumping of H plus back in harness it in order to do phosphorylation of AD P, this will help to generate a TP. So here D is the correct answer.
4
Problem
Problem
All of the following pump H+ ions across the inner membrane of mitochondria except:
A
Complex I
B
Complex II
C
Complex III
D
Complex IV
E
Complex V
5
Problem
Problem
Chemiosmotic creation of ATP is driven by which?
A
ATP Synthase complex.
B
Oxidative phosphorylation of ADP.
C
Large quantities of ADP in the mitochondrial matrix.
D
Potential energy of H+ ion concentration gradient created by ETC.
Do you want more practice?
We have more practice problems on Oxidative Phosphorylation