Enzyme responsible for decarboxylation and phosphate transfer in the same gluconeogenic reaction is:

• A. Tyrosine kinase
• B. Oxaloacetate carboxykinase
• C. Pyruvate kinase
• D. Phosphoenolpyruvate carboxykinase
• E. Phosphofructokinase

Answer: (D)

Verified step by step guidance

1. Understand the context of the problem: The question is asking about an enzyme involved in gluconeogenesis, specifically one that performs decarboxylation and phosphate transfer.
2. Identify the process: Gluconeogenesis is the metabolic pathway that results in the generation of glucose from non-carbohydrate substrates. It involves several enzymes that catalyze different reactions.
3. Focus on the reaction types: Decarboxylation is the removal of a carboxyl group, releasing carbon dioxide (CO2). Phosphate transfer involves the transfer of a phosphate group from one molecule to another.
4. Review enzyme functions: Phosphoenolpyruvate carboxykinase (PEPCK) is known for catalyzing the conversion of oxaloacetate to phosphoenolpyruvate, involving both decarboxylation and phosphate transfer.
5. Eliminate incorrect options: Tyrosine kinase is involved in phosphorylation of proteins, not gluconeogenesis. Pyruvate kinase is involved in glycolysis, not gluconeogenesis. Phosphofructokinase is also involved in glycolysis.