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Ch. 11 - Gene Mutation, DNA Repair, and Homologous Recombination

Chapter 11, Problem 5

In March 2011 an earthquake measuring approximately 9.0 on the Richter scale struck Fukushima, Japan. Several nuclear reactors at the Fukushima Daichii Nuclear Power Plant were damaged, and nuclear core meltdown occurred. A massive release of radiation accompanied damage to the plant, and 5 years later the incidence of thyroid cancer in children exposed to the radiation was determined to be well over 100 times more frequent than expected without radiation exposure. DNA damage and mutations resulting from radiation exposure are suspected of causing this increased cancer rate. What gene discussed in this chapter might be responsible for pausing the cell cycle of dividing cells long enough for radiation-induced damage to be repaired in cells?

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