Ch. 21 - Genomic Analysis
Chapter 20, Problem 17
Metagenomics studies generate very large amounts of sequence data. Provide examples of genetic insight that can be learned from metagenomics.
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What functional information about a genome can be determined through applications of chromatin immunoprecipitation (ChIP)?
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We all carry about 20,000 genes in our genome. So far, patents have been issued for more than 6000 of these genes. Do you think that companies or individuals should be able to patent human genes? Why or why not?
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It can be said that modern biology is experiencing an 'omics' revolution. What does this mean? Explain your answer.
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What are DNA microarrays? How are they used?
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Annotation of the human genome sequence reveals a discrepancy between the number of protein-coding genes and the number of predicted proteins actually expressed by the genome. Proteomic analysis indicates that human cells are capable of synthesizing more than 100,000 different proteins and perhaps three times this number. What is the discrepancy, and how can it be reconciled?
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Textbook Question
In Section 21.10 we briefly discussed the Human Proteome Map (HPM). An interactive Web site for the HPM is available at http://www.humanproteomemap.org. Visit this site, and then answer the questions in parts (a) and (b) and complete part (c).
How many proteins were identified in this project?
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