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Ch. 21 - Genomic Analysis

Chapter 20, Problem 9

What functional information about a genome can be determined through applications of chromatin immunoprecipitation (ChIP)?

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Hello, everyone and welcome to today's video. So which of the following option correctly describes the applications of chip. And remember from previous videos that chip is going to stand for Chrome 18 immuno precipitation. And it is this technique that allows us to pinpoint DNA that has proteins bound to and localize them in the cell. Now let's go over each of our answer choices to see what we could do with this method. Well, first of all, it is used for locating transcription factor binding sites. Remember that these proteins could be acting as transcription factors. So it is true and we're going to not cancel it out because it is a correct answer choice. Let's move on to answer choice B it is applied to study epigenetic modifications or remember that epigenetic refers to the modifications of certain DNA sequence that affect their expression. If there are certain proteins that are bound to the DNA sequence, and we can study how they are bound to it, then we can study epigenetic modifications. This is correct as well and we're not going to cancel it out. And then it is used to characterize chromatic structure or remember that protein can be either chromatic or head or chromatic. And it depends on what is bound to it. And the epic genetic modifications that it has, we already stated that we are able to study epigenetic modifications using these techniques. So we can definitely also characterize promoting structure because of this. This is going to be correct as well. So we were not able to cancel out any of these answer choices. So the correct answer choice here is going to be answer choice. I really hope this video helped you and I hope to see you on the next one.