Skip to main content
Ch. 21 - Genomic Analysis

Chapter 20, Problem 4

Compare and contrast WGS to a map-based cloning approach.

Verified Solution
Video duration:
2m
This video solution was recommended by our tutors as helpful for the problem above.
229
views
Was this helpful?

Video transcript

Hey everyone. Let's take a look at this question together. Which of the following statements about whole genome sequencing is true. So what do we know about whole genome sequencing When we know that it allows the sequencing and assembling of the whole gino. And we know that it is also referred to as shotgun sequencing. And this is because multiple copies of the entire chromosome are cut into short and overlapping fragments. And we know that the whole genome sequencing process includes D. N. A. Shearing D. N. A. Barcoding D. N. A. Sequencing. And lastly it involves data analysis. And so now that we have these points about whole genome sequencing written down, let's take a look at the answer choices to figure out which of the following statements is true. Well we can see answer choice A says they can identify small numbers of genes at a time which we know is incorrect since it allows the sequencing and assembling of the whole genome, it would identify large numbers of genes at the same time. So answer choice A. Is incorrect. Answer choice B says it involves cutting DNA into smaller pieces. Which another term for this is that D. N. A. Sharing which we know that it is included in whole genome sequencing. So answer choice B is a true statement about whole genome sequencing and answer choice C. Is incorrect because we know that we do not use gel electrophoresis. So it cannot be answer choices C. Or answer choice D. And answer choice B is the only true statement here about whole genome sequencing. I hope you found this video to be helpful. Thank you and goodbye.
Related Practice
Textbook Question
In this chapter, we focused on a number of interesting applications of genetic engineering, genomics, and biotechnology. At the same time, we found many opportunities to consider the methods and reasoning by which much of this information was acquired. From the explanations given in the chapter, what answers would you propose to the following fundamental questions? How can we correlate the genome with RNA expression data in a tissue or a single cell?
246
views
Textbook Question

Write a short essay that explains how recombinant DNA techniques were used to identify and study genes compared to how modern genomic techniques have revolutionized the cloning and analysis of genes.

247
views
Textbook Question

What is functional genomics? How does it differ from comparative genomics?

236
views
Textbook Question

The genetic difference between two Drosophila species, D. heteroneura and D. silvestris, as measured by nucleotide diversity, is about 1.8 percent. The difference between chimpanzees (Pan troglodytes) and humans (H. sapiens) is about the same, yet the latter species is classified in a different genera. In your opinion, is this valid? Explain why.

225
views
Textbook Question

What is bioinformatics, and why is this discipline essential for studying genomes? Provide two examples of bioinformatics applications.

205
views
Textbook Question

Sequencing the human genome, the development of microarray technology, and personal genomics promise to improve our understanding of normal and abnormal cell behavior. How are these approaches dramatically changing our understanding and treatment of complex diseases such as cancer?

246
views