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Ch. 16 - Regulation of Gene Expression in Bacteria

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Klug 12th Edition

Ch. 16 - Regulation of Gene Expression in Bacteria

Problem 13

Chapter 16, Problem 13

Attenuation of the trp operon was viewed as a relatively inefficient way to achieve genetic regulation when it was first discovered in the 1970s. Since then, however, attenuation has been found to be a relatively common regulatory strategy. Assuming that attenuation is a relatively inefficient way to achieve genetic regulation, what might explain its widespread occurrence?

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Hello, everyone here. We have a question that says, during the translation attenuation and bacteria. The blank, which specifies the site for ribosome binding, allowing proper translation is sequestered, and our answer here is D the Schindel Garneau sequence. And what this result in is the inability of the ribosomes complexes to form and the translation process is impaired. Thank you for watching. Bye.

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Related Practice

Textbook Question

Predict the effect on the inducibility of the lac operon of a mutation that disrupts the function of (a) the crp gene, which encodes the CAP protein, and (b) the CAP-binding site within the promoter.

Textbook Question

Erythritol, a natural sugar abundant in fruits and fermenting foods, is about 65 percent as sweet as table sugar and has about 95 percent fewer calories. It is 'tooth friendly' and generally devoid of negative side effects as a human consumable product. Pathogenic Brucella strains that catabolize erythritol contain four closely spaced genes, all involved in erythritol metabolism. One of the four genes (eryD) encodes a product that represses the expression of the other three genes. Erythritol catabolism is stimulated by erythritol. Present a simple regulatory model to account for the regulation of erythritol catabolism in Brucella. Does this system appear to be under inducible or repressible control?

Textbook Question

Describe the role of attenuation in the regulation of tryptophan biosynthesis.

Textbook Question

Neelaredoxin is a 15-kDa protein that is a gene product common in anaerobic bacteria. It has superoxide-scavenging activity, and it is constitutively expressed. In addition, its expression is not further induced during its exposure to O₂ or H₂O₂ [Silva, G. et al. (2001). J. Bacteriol. 183:4413–4420]. What do the terms constitutively expressed and induced mean in terms of neelaredoxin synthesis?

Textbook Question

The creation of milk products such as cheeses and yogurts is dependent on the conversion by various anaerobic bacteria, including several Lactobacillus species, of lactose to glucose and galactose, ultimately producing lactic acid. These conversions are dependent on both permease and β-galactosidase as part of the lac operon. After selection for rapid fermentation for the production of yogurt, one Lactobacillus subspecies lost its ability to regulate lac operon expression [Lapierre, L., et al. (2002). J. Bacteriol. 184:928–935]. Would you consider it likely that in this subspecies the lac operon is on or off? What genetic events would likely contribute to the loss of regulation as described above?

Textbook Question

Both attenuation of the trp operon in E. coli and riboswitches in B. subtilis rely on changes in the secondary structure of the leader regions of mRNA to regulate gene expression. Compare and contrast the specific mechanisms in these two types of regulation with that involving short noncoding RNAs (sRNAs).