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Ch. 15 - Gene Mutation, DNA Repair, and Transposition

Chapter 15, Problem 9

In studies of the amino acid sequence of wild-type and mutant forms of tryptophan synthetase in E. coli, the following changes have been observed: Determine a set of triplet codes in which only a single-nucleotide change produces each amino acid change.

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Hello everyone and welcome to today's video. So which of the following point mutations results in a code in that calls for a different amino acid. So it turns out that we have many different types of point mutations in which a nucleoside is replaced by another, resulting in many different consequences. Well, let's go over each of these point mutations so that we may solve this problem. Let's begin by answer choices C and D. Because in each of these point mutations we're going to get a code on or an amino acid which is the same as the one that we have. Prior. It is not going to result in a different amino acids. So we're going to cancel this out in a nonsense mutation again here. This is a point mutation that results in a stop coding. It is not going to result in a different amino acid. It is instead going to stop translation. So we're going to cancel it out again because it's not really what we're looking for. And then we have a missing mutation. Well here mrs mutations actually going to result in a different amino acid is the one that we have prior to the mutation occurring because of this. This is perfectly going to describe what the question is asking for and we're going to highlight answer choice. A nuisance mutation as a correct answer to our question. I really hope this helped you and I hope to see you on the next one