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Ch. 14 - Translation and Proteins

Chapter 14, Problem 6

In a coding experiment using repeating copolymers (as demonstrated in Table 13.3), the following data were obtained: Copolymer Codons Produced Amino Acids in Polypeptide AG AGA, GAG Arg, Glu AAG AGA, AAG, GAA Lys, Arg, Glu AGG is known to code for arginine. Taking into account the wobble hypothesis, assign each of the four codons produced in the experiment to its correct amino acid.

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Hi everyone. Let's look at our next question here. It says which nucleotide of the code on is degenerate according to the wobble hypothesis? Well, the wobble hypothesis theorizes that the pairing between one of the nucleotides in code on is a little looser more flexible than the pairing with the other two nucleotides. That allows more than one code into code for the same amino acid. Um That's the meaning of degenerate meaning that you have multiple code and that code for the same amino acid so which we need to determine which nucleotide that is. And the answer is that the third nucleotide in that cotton is less rigid in its findings in the first two, allowing that anti coding of the T. N R T E R N. A. To pair with more than one M. RNA sequence. Since it has some flexibility in that third nucleotide. So our answer here is gonna be choice e. 3rd. The 1st and 2nd have to be very specific in their binding and choice D. Is also incorrect since the second has to be specific. But the third has some flexibility. And that's where you get that phenomenon of multiple code ons coding for the same amino acid in the next video