Ch. 14 - Translation and Proteins
Chapter 14, Problem 6
The α chain of eukaryotic hemoglobin is composed of 141 amino acids. What is the minimum number of nucleotides in an mRNA coding for this polypeptide chain?
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Textbook Question
In studies using repeating copolymers, AC . . . incorporates threonine and histidine, and CAACAA . . . incorporates glutamine, asparagine, and threonine. What triplet code can definitely be assigned to threonine?
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Textbook Question
During translation, what molecule bears the codon? the anticodon?
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Textbook Question
In a coding experiment using repeating copolymers (as demonstrated in Table 13.3), the following data were obtained:
Copolymer Codons Produced Amino Acids in Polypeptide
AG AGA, GAG Arg, Glu
AAG AGA, AAG, GAA Lys, Arg, Glu
AGG is known to code for arginine. Taking into account the wobble hypothesis, assign each of the four codons produced in the experiment to its correct amino acid.
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Textbook Question
In the triplet binding technique, radioactivity remains on the filter when the amino acid corresponding to the codon is labeled. Explain the rationale for this technique.
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Textbook Question
Assuming that each nucleotide in an mRNA is 0.34 nm long, how many triplet codes can simultaneously occupy the space in a ribosome that is 20 nm in diameter?
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Textbook Question
Describe the central dogma of molecular genetics and how it serves as the basis of modern genetics.
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