Chapter 13, Problem 18
What observations suggested the existence of mRNA?
Video transcript
Research indicates that promoters may fall into one of two classes: focused or dispersed. How do these classes differ, and which genes tend to be associated with each?
Define the process of transcription. Where does this process fit into the central dogma of molecular biology (DNA makes RNA makes protein)?
Explain the features of the Initiator (Inr) elements, BREs, DPEs, and MTEs of focused promoters.
Many transcriptional activators are proteins with a DNA-binding domain (DBD) and an activation domain (AD). Explain how each domain contributes to transcriptional initiation. Would you expect repressors to also have each of these domains?
Describe the structure of RNA polymerase in bacteria. What is the core enzyme? What is the role of the σ subunit?
How do the ENCODE data vastly help determine which enhancers regulate which genes?