Refer to Table 13.1. Can you hypothesize why a synthetic RNA composed of a mixture of poly U  poly A would not stimulate incorporation of ¹⁴C-phenylalanine into protein?

Video transcript

Hi everyone. Let's take a look at this practice problem together. Why is pre M. R. N. A. Often longer than mature M. R. N. A. In new carry outs recall that in new carry outs. D. N. A. Is transcribed to produce pre M. R. N. A. That undergoes further processing and modification to become the mature M. R. N. A. And the mature M. RNA is the more stable form and is used for translation. So why is the pre M. R. N. A. Often longer? Is it a due to mutations? That is not a correct answer? We know that mutations are not involved in the processing of the pre M. R. N. A. Is the answer be due to RNA digestion by some enzymes. Now we know that enzymes are important in processing pre M. R. N. A. However their function is not digestion but rather modify modification so they modify the pre M. RNA and add things onto it like the five crime cap and the Polly A. Tell. However this still does not account for the longer length of pre M. R. N. A. So B is also incorrect. Is it C due to intron removal recall that pre M. R. N. A is made up of both coding and non coding sequences which are exxons and introns respectively. So the introns are non coding and during processing the introns are excised out. So that takes out whole sequences making the mature M. RNA to be shorter than the pre M. R. N. A. So the correct answer is C. Due to intron removal and therefore D. Is also incorrect. Alright, everybody, I hope you found this helpful, and I'll see you soon for the next practice problem.