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04:01Evaluate the following statements related to the synthesis of nucleic acids. Select True or False for each statement. T/F Ribonucleotides are added to the 3′ end of a DNA strand. T/F Polymerization of nucleic acids occurs by the formation of phosphodiester bonds. T/F Complementary pairing between sugars is required for copying nucleic acids. T/F Strands in a double helix are synthesized in an antiparallel orientation.
Single strands of nucleic acids are directional, meaning that there are two different ends. What functional groups define the two different ends of a strand?
What is responsible for the increased stability of DNA compared to RNA?
What would be the sequence of the strand of DNA that is made from the following template: 5′-GATATCGAT-3′? (Your answer must be written 5'→3'.) How would the sequence be different if RNA were made from this DNA template?
According to the RNA world model, a ribozyme would replicate by creating a double-stranded RNA intermediate. Would you expect the intermediate to have the same catalytic activity as the original ribozyme? Justify your answer with an explanation.
Make a concept map (see BioSkills 12) that relates DNA's primary structure to its secondary structure. Your diagram should include deoxyribonucleotides, base-stacking interactions, purines, pyrimidines, phosphodiester linkages, DNA's primary structure, DNA's secondary structure, complementary base pairing, and antiparallel double helix.
