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Ch.4 - Nucleic Acids and the RNA World

Chapter 4, Problem 8

According to the RNA world model, a ribozyme would replicate by creating a double-stranded RNA intermediate. Would you expect the intermediate to have the same catalytic activity as the original ribozyme? Justify your answer with an explanation.

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Video transcript

Hello everyone. And in today's video we have the following problem. So what is not true regarding the RNA world model? So remember that we're looking for the incorrect statement among our answer choices. So keep that in mind as we solve the problem in case you forgot. I want to help. Do you recall what the RNA world model or the RNA world hypothesis states? And it states that earlier life forms use RNA alone to store genetic information. So only RNA was president. There was no DNA or proteins present at the moment. So it's a very important hypothesis now that we're going to use it to solve the problem. Beginning by answer choice. A rivals times are catalytic RNA that can perform catalytic activity like enzymes. So remember that back then we did not have proteins. We did not have enzymes. So these cells or these life forms had to rely on R. N. A. To perform the activities of enzymes. And these RNA molecules that were performing these activities will call rivals times. This is a correct statement. Since we're looking for the incorrect when we're going to cancel this out. So answer choice B states life later evolved to use DNA and proteins instead of RNA. Well, D. N. A. Is a much more stable molecule than RNA. Since it is more stable cells prefer it in order to store genetic information because they want that information to not be disturbed as much as possible. So this is actually a correct statement. We started using DNA after RNA because it was a more stable molecule. And in turn this is going to make answer choice C. A correct statement as well. DNA is in fact more stable than RNA and that's why we use it to store genetic information. This is a correct statement as well. This all leaves us with answer choice D. A ribosome which like we said, is an R. N. A. Just a catalytic RNA molecule with a double stranded RNA template is more catalytic than a single stranded RNA. So a single stranded RNA just portrays tertiary structure. Well, a repossession with a double stranded RNA portrays quite ordinary structure. These catalytic um just use of the RNA molecule is going to require or is going to be more showcase in RNA molecules that have tertiary structure. So this makes the single stranded RNA molecules more effective at this catalytic action than the double stranded one. Because of this is going to make answer choice. The incorrect or the not true statement that we're looking for. And we're going to highlight it as the final answer to our question. So I really hope this video helped you and I hope to see you on the next one