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Ch. 9 Muscles and Muscle Tissue
Chapter 8, Problem 11

The ions that enter the skeletal muscle cell during the generation of an action potential are a. calcium ions, b. chloride ions, c. sodium ions, d. potassium ions.

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1
Identify the role of ions in generating an action potential in skeletal muscle cells.
Recall that action potentials in neurons and muscle cells are primarily initiated by the movement of sodium (Na^+) ions.
Understand that during the depolarization phase of an action potential, sodium channels open, allowing Na^+ ions to enter the cell.
Recognize that the influx of Na^+ ions causes the inside of the cell to become more positive, leading to depolarization.
Conclude that the ions entering the skeletal muscle cell during the generation of an action potential are sodium ions.

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Key Concepts

Here are the essential concepts you must grasp in order to answer the question correctly.

Action Potential

An action potential is a rapid, temporary change in the electrical membrane potential of a cell, particularly in neurons and muscle cells. It occurs when a stimulus causes the membrane to depolarize, leading to the opening of voltage-gated ion channels. This process is essential for the transmission of signals in the nervous system and the contraction of muscle fibers.
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Action Potential

Ion Channels

Ion channels are specialized proteins embedded in the cell membrane that allow specific ions to pass in and out of the cell. During an action potential, sodium (Na+) channels open first, allowing sodium ions to flow into the cell, which contributes to depolarization. Other ion channels, such as potassium (K+) and calcium (Ca2+), play roles in repolarization and muscle contraction.
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Ions - Sodium and Potassium Example 3

Skeletal Muscle Contraction

Skeletal muscle contraction is initiated by the influx of calcium ions into the muscle cell, which triggers the interaction between actin and myosin filaments. However, during the generation of an action potential, sodium ions are primarily responsible for depolarizing the membrane. Understanding the role of these ions is crucial for comprehending how muscle contractions are controlled and executed.
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Overview of Muscle Contraction