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Ch. 3 The Cell

Chapter 3, Problem 3.17a

Which of the following is not a phase of mitosis?


a. Interphase

b. Prophase

c. Anaphase

d. Metaphase

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Hi, everyone. Let's take a look at this practice problem together. During which phase of mitotic cell division do sister chromatid split at the centromere transforming into individual chromosomes. The answer options are a metaphase b telophase, C cytokinesis and D anaphase. So to help us answer this question, I am putting up a drawing of a cell going through each stage of mitosis. So let's go ahead and talk through this drawing together. Recall that mitosis begins with prophet. Now, during this phase, the chromatin condense, the nuclear envelope disappears and then you have spindle assembly. The next stage is metaphase and metaphase is a short stage and this is when the chromosomes line up at the equator of the cell. After metaphase, there's anaphase during this phase, the sister chromatid are pulled apart and drawn to opposite sides of the cell. And the last phase is telophase. Here, the chromosomes uncoil, the mitotic spindle disappears and that nuclear envelope is formed again. Now, option c cytokine cytokinesis is not pictured in this drawing. However, if this is the process of cytoplasm division and it occurs during late anaphase and telophase, it is not the phase where the sister chromatid split. So we can eliminate option C. So which phase is where those sister chromatid split? It's an a phase in, in anaphase. That's when the chromatid are pulled apart at the centromere. And they now become the individual chromosomes. And then eventually you get the two new daughter cells at the end of mitosis. So the correct answer is option D anaphase. All right, everyone. I hope you found this helpful and I'll see you soon for the next practice problem.