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Ch. 16 The Endocrine System
Chapter 16, Problem 16.14a

Cortisol is:


a. a potent inhibitor of the inflammatory response.
b. an important part of the stress response.
c. Both a and b are correct.
d. Neither a nor b is correct.

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1
Identify the role of cortisol in the body, focusing on its functions related to inflammation and stress.
Understand that cortisol is a glucocorticoid hormone produced by the adrenal cortex.
Recognize that cortisol plays a significant role in the body's response to stress by increasing blood sugar, suppressing the immune system, and aiding in metabolism.
Acknowledge that cortisol has anti-inflammatory properties, which means it can inhibit the inflammatory response.
Evaluate the options given: a) cortisol inhibits inflammation, b) cortisol is part of the stress response, c) both a and b are correct, d) neither a nor b are correct.

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Key Concepts

Here are the essential concepts you must grasp in order to answer the question correctly.

Cortisol and Inflammation

Cortisol is a steroid hormone produced by the adrenal glands, primarily in response to stress. It plays a crucial role in regulating the body's inflammatory response by inhibiting the production of inflammatory mediators. This action helps to prevent excessive inflammation, which can lead to tissue damage and various health issues.
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Inflammation

Cortisol and the Stress Response

Cortisol is a key component of the body's stress response, often referred to as the 'fight or flight' response. When faced with stress, cortisol levels increase, leading to various physiological changes such as elevated blood sugar levels and enhanced metabolism. This prepares the body to respond effectively to perceived threats.
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Dual Role of Cortisol

Cortisol has a dual role in the body, acting both as an anti-inflammatory agent and as a critical hormone in the stress response. Understanding this duality is essential for comprehending its effects on health, as chronic high levels of cortisol can lead to negative outcomes, including immune suppression and increased risk of chronic diseases.
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The Hypothalamus and Pituitary Gland Example 2
Related Practice
Textbook Question

Which of the following statements correctly describes the role of parathyroid hormone?


a. Parathyroid hormone regulates the metabolic rate.

b. Parathyroid hormone increases the blood calcium ion concentration.

c. Parathyroid hormone decreases the blood sodium ion concentration.

d. Parathyroid hormone causes water retention by the kidneys.

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Textbook Question

Fill in the blanks: The outer part of the adrenal gland is the______, which secretes______. The inner part of the adrenal gland is the_____ , which secretes _______.

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Textbook Question

Which of the following is not an effect of aldosterone?


a. Increased excretion of hydrogen ions from the fluid in the kidneys

b. Increased retention of sodium ions from the fluid in the kidneys

c. Increased retention of potassium ions from the fluid in the kidneys

d. Increased retention of water from the fluid in the kidneys

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Textbook Question

Describe the components of the hypothalamic-pituitary-adrenocortical axis, and explain how it regulates secretion from the adrenal gland.

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Textbook Question

Which of the following hormones is not an integral part of the stress response?


a. Epinephrine

b. Cortisol

c. Insulin

d. Glucagon

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Textbook Question

Which of the following statements about the adrenal medulla is false?


a. Secretion from the adrenal medulla is triggered by ACTH and the sympathetic nervous system.

b. The adrenal medulla consists of glandular epithelial cells.

c. The adrenal medulla is a modified postsynaptic sympathetic ganglion.

d. The products of the adrenal medulla prolong the effects of the sympathetic response.

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