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Ch. 8 - Microbial Genetics
Chapter 8, Problem 8.9a

Two offspring cells are most likely to inherit which one of the following from the parent cell?
a. a change in a nucleotide in mRNA
b. a change in a nucleotide in tRNA
c. a change in a nucleotide in rRNA
d. a change in a nucleotide in DNA
e. a change in a protein

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1
Understand that inheritance involves the transfer of genetic information from parent to offspring.
Recognize that mRNA, tRNA, and rRNA are types of RNA involved in protein synthesis and are not directly inherited.
Identify that DNA is the molecule that carries genetic information and is passed from parent to offspring during cell division.
Consider that changes in DNA, such as mutations, can be inherited by offspring cells.
Conclude that a change in a nucleotide in DNA is most likely to be inherited by offspring cells.

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Key Concepts

Here are the essential concepts you must grasp in order to answer the question correctly.

DNA Replication

DNA replication is the biological process by which a cell makes an identical copy of its DNA. This process is crucial during cell division, ensuring that each offspring cell receives a complete set of genetic information. Mutations or changes in the nucleotide sequence of DNA can be passed on to the next generation, making it a key factor in inheritance.
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Types of RNA

There are several types of RNA, including mRNA (messenger RNA), tRNA (transfer RNA), and rRNA (ribosomal RNA). While mRNA carries genetic information from DNA to ribosomes for protein synthesis, tRNA helps in translating that information into proteins. rRNA is a structural component of ribosomes. Changes in these RNA types do not directly affect the genetic inheritance of offspring cells.
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Protein Synthesis

Protein synthesis is the process by which cells generate proteins based on the genetic instructions carried by mRNA. This involves transcription (copying DNA to mRNA) and translation (decoding mRNA to form a protein). While proteins are essential for cellular functions, changes in proteins themselves are not inherited; rather, the genetic code that dictates protein synthesis is inherited through DNA.
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