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Ch. 5 - Microbial Metabolism
Chapter 5, Problem 5.5a

Which of the following is the best definition of the Krebs cycle?
a. the oxidation of pyruvic acid
b. the way cells produce CO₂
c. a series of chemical reactions in which NADH is produced from the oxidation of pyruvic acid
d. a method of producing ATP by phosphorylating ADP
e. a series of chemical reactions in which ATP is produced from the oxidation of pyruvic acid

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1
Identify the main purpose of the Krebs cycle in cellular respiration.
Understand that the Krebs cycle is a series of chemical reactions.
Recognize that the Krebs cycle involves the oxidation of pyruvic acid.
Determine which molecules are produced during the Krebs cycle, such as NADH and ATP.
Compare the options to see which one best describes the series of reactions and their products.

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Key Concepts

Here are the essential concepts you must grasp in order to answer the question correctly.

Krebs Cycle Overview

The Krebs cycle, also known as the citric acid cycle or TCA cycle, is a series of enzymatic reactions that occur in the mitochondria of cells. It plays a crucial role in cellular respiration by oxidizing acetyl-CoA, derived from carbohydrates, fats, and proteins, to produce energy carriers such as NADH and FADH2, as well as carbon dioxide as a waste product.
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Role of NADH

NADH is a key electron carrier produced during the Krebs cycle. It is generated when NAD+ accepts electrons during the oxidation of substrates, such as pyruvic acid. The NADH produced is then utilized in the electron transport chain to generate ATP, highlighting its importance in energy metabolism.
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Guided course
05:22
Electron Carriers:NADH & FADH2

ATP Production

ATP, or adenosine triphosphate, is the primary energy currency of the cell. While the Krebs cycle itself does not produce a large amount of ATP directly, it generates high-energy electron carriers (NADH and FADH2) that are essential for the oxidative phosphorylation process, where the majority of ATP is synthesized in cellular respiration.
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