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Ch. 2 - Chemical Principles
Chapter 2, Problem 8.3a

Match the following examples of mutagens. <IMAGE>

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Identify the types of mutagens presented in the image. Common categories include chemical mutagens, physical mutagens, and biological mutagens.
For chemical mutagens, look for examples such as base analogs, alkylating agents, or intercalating agents. These can cause changes in the DNA sequence by mimicking bases or altering the DNA structure.
For physical mutagens, identify examples like UV radiation or ionizing radiation. These can cause DNA damage through the formation of thymine dimers or breaks in the DNA strands.
For biological mutagens, consider examples such as transposons or viruses. These can insert themselves into the genome, disrupting normal gene function.
Match each example from the image to the appropriate category of mutagen based on their characteristics and mechanisms of action.

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Key Concepts

Here are the essential concepts you must grasp in order to answer the question correctly.

Mutagens

Mutagens are agents that cause changes or mutations in the DNA sequence of an organism. These can be physical agents like radiation, chemical agents like certain drugs or pollutants, or biological agents such as viruses. Understanding how mutagens interact with DNA is crucial for studying genetic variation, cancer development, and evolutionary processes.
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Types of Mutagens

Mutagens can be classified into two main categories: chemical mutagens and physical mutagens. Chemical mutagens include substances that can alter DNA structure, such as alkylating agents and intercalating agents. Physical mutagens, on the other hand, include ionizing radiation (like X-rays) and non-ionizing radiation (like UV light), which can cause direct DNA damage.
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DNA Repair Mechanisms

Cells have evolved various DNA repair mechanisms to correct mutations caused by mutagens. These include direct repair, base excision repair, nucleotide excision repair, and mismatch repair. Understanding these mechanisms is essential for comprehending how organisms maintain genetic stability and how failures in these systems can lead to diseases such as cancer.
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Related Practice
Textbook Question

The term trace elements refers to

a. the elements CHONPS.

b. vitamins.

c. nitrogen, phosphorus, and sulfur.

d. small mineral requirements.

e. toxic substances.

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Textbook Question

Briefly describe the components of DNA, and explain its functional relationship to RNA and protein.

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Textbook Question

Identify and mark each of the following on the portion of DNA undergoing replication: replication fork, DNA polymerase, RNA primer, parent strands, leading strand, lagging strand, the direction of replication on each strand, and the 5′ end of each strand. <IMAGE>

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Textbook Question

The following is a code for a strand of DNA.<IMAGE>


a. Using the genetic code provided in Figure 8.8, fill in the blanks to complete the segment of DNA shown.

b. Fill in the blanks to complete the sequence of amino acids coded for by this strand of DNA.

c. Write the code for the complementary strand of DNA completed in part (a).

d. What would be the effect if C were substituted for T at base 10?

e. What would be the effect if A were substituted for G at base 11?

f. What would be the effect if G were substituted for T at base 14?

g. What would be the effect if C were inserted between bases 9 and 10?

h. How would UV radiation affect this strand of DNA?

i. Identify a nonsense sequence in this strand of DNA.

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Textbook Question

Which sequence is the best target for damage by UV radiation: AGGCAA, CTTTGA, or GUAAAU? Why aren’t all bacteria killed when they are exposed to sunlight?

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Textbook Question

Outline the treatment process for drinking water.

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