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Ch. 2 - Chemical Principles
Chapter 2, Problem 8.1a

Briefly describe the components of DNA, and explain its functional relationship to RNA and protein.

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DNA, or deoxyribonucleic acid, is composed of nucleotides, each consisting of a sugar (deoxyribose), a phosphate group, and a nitrogenous base (adenine, thymine, cytosine, or guanine).
The structure of DNA is a double helix, where two strands are held together by hydrogen bonds between complementary bases (A-T and C-G).
DNA serves as the genetic blueprint for organisms, storing the instructions needed to build and maintain cells.
The process of transcription involves copying a segment of DNA into RNA (ribonucleic acid), which is similar to DNA but contains ribose sugar and uracil instead of thymine.
RNA is then translated into proteins, which are chains of amino acids that fold into specific shapes to perform various functions in the cell, thus linking DNA to protein synthesis.

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Key Concepts

Here are the essential concepts you must grasp in order to answer the question correctly.

Components of DNA

DNA, or deoxyribonucleic acid, is composed of four nucleotide bases: adenine (A), thymine (T), cytosine (C), and guanine (G). These bases pair specifically (A with T and C with G) to form the double helix structure. Additionally, DNA contains a sugar (deoxyribose) and a phosphate group, which together form the backbone of the molecule. The sequence of these bases encodes genetic information essential for the development and functioning of living organisms.
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Components of DNA Replication

Transcription and RNA

Transcription is the process by which the genetic information in DNA is copied into messenger RNA (mRNA). During this process, RNA polymerase synthesizes a single strand of RNA using one of the DNA strands as a template. This mRNA then carries the genetic code from the nucleus to the ribosomes, where it serves as a template for protein synthesis. The relationship between DNA and RNA is crucial for gene expression and regulation.
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Initiation of Transcription

Translation and Protein Synthesis

Translation is the process by which the sequence of nucleotides in mRNA is translated into a sequence of amino acids, forming a protein. This occurs at the ribosome, where transfer RNA (tRNA) molecules bring specific amino acids to the growing polypeptide chain based on the codons in the mRNA. The functional relationship between RNA and proteins is fundamental, as proteins perform most cellular functions and are essential for the structure and regulation of the body's tissues and organs.
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Related Practice
Textbook Question

DRAW IT Draw a simple lipid, and show how it could be modified to a phospholipid.

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Textbook Question

Macronutrients (needed in relatively large amounts) are often listed as CHONPS. What does each of these letters indicate, and why are they needed by the cell?

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Textbook Question

The term trace elements refers to

a. the elements CHONPS.

b. vitamins.

c. nitrogen, phosphorus, and sulfur.

d. small mineral requirements.

e. toxic substances.

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Textbook Question

Identify and mark each of the following on the portion of DNA undergoing replication: replication fork, DNA polymerase, RNA primer, parent strands, leading strand, lagging strand, the direction of replication on each strand, and the 5′ end of each strand. <IMAGE>

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Textbook Question

Match the following examples of mutagens. <IMAGE>

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Textbook Question

The following is a code for a strand of DNA.<IMAGE>


a. Using the genetic code provided in Figure 8.8, fill in the blanks to complete the segment of DNA shown.

b. Fill in the blanks to complete the sequence of amino acids coded for by this strand of DNA.

c. Write the code for the complementary strand of DNA completed in part (a).

d. What would be the effect if C were substituted for T at base 10?

e. What would be the effect if A were substituted for G at base 11?

f. What would be the effect if G were substituted for T at base 14?

g. What would be the effect if C were inserted between bases 9 and 10?

h. How would UV radiation affect this strand of DNA?

i. Identify a nonsense sequence in this strand of DNA.

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