DRAW IT Label on the figure the following processes that result in phagocytosis: margination, diapedesis, adherence, and phagolysosome formation.
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Verified step by step guidance

1. Identify the process of margination, where white blood cells move to the edges of blood vessels in response to chemical signals.
2. Label diapedesis, which is the movement of white blood cells through the blood vessel walls into the surrounding tissue.
3. Mark adherence, the process where phagocytes attach to the pathogens or debris.
4. Indicate phagolysosome formation, where the phagosome containing the pathogen fuses with a lysosome to digest the pathogen.
5. Ensure each process is clearly labeled on the figure to show the sequence leading to phagocytosis.

Key Concepts

Phagocytosis

Phagocytosis is a cellular process in which certain cells, known as phagocytes, engulf and digest foreign particles, bacteria, or dead cells. This process is crucial for the immune response, allowing the body to eliminate pathogens and debris. Phagocytes recognize and bind to these targets, leading to their internalization and subsequent destruction within specialized compartments.

Margination and Diapedesis

Margination refers to the process where white blood cells move to the periphery of blood vessels during inflammation. Diapedesis is the subsequent step where these cells squeeze through the endothelial cell junctions to exit the bloodstream and enter the tissue. Together, these processes facilitate the rapid recruitment of immune cells to sites of infection or injury.

Phagolysosome Formation

Phagolysosome formation occurs when a phagosome, which is a vesicle containing the engulfed material, fuses with a lysosome, an organelle filled with digestive enzymes. This fusion creates a phagolysosome, where the engulfed material is broken down and digested. This step is essential for the effective clearance of pathogens and the resolution of inflammation.